Structure of PDB 8ui8 Chain A Binding Site BS01

Receptor Information

>8ui8 Chain A (length=643) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SFQRVVHVQQKDDGCCLWHLKPPSCPLLTKFKELNTKVIDLSKCGIALGE
FSTLNSKLKSGNSAAVFMRTRKEFTEEVRNLLLEEIRWSNPEFSLKKYFP
LLLKKQITEDMLWTEKYQPQTASELIGNELAIKKLHSWLKDWKRRAELEE
RQNLKGKEEESRLCNTVLITGPTGVGKTAAVYACAQELGFKIFEVNASSQ
RSGRQILSQLKEATQSHQVDKQGVNSQKPCFFNSKNATSLILFEEVDVIF
DEDAGFLNAIKTFMATTKRPVILTTSDPTFSLMFDGCFEEIKFSTPSLLN
VASYLQMICLTENFRTDVKDFVTLLTANTCDIRKSILYLQFWIRSGGGVL
EERPLTLLPKCDSGCAETLFGLKNIFSPSEDLFSFLKHKITMKEEWHKFI
QLLTEFQMRNVDFLYSNLEFILPLPVDTIPTTAGKKCSALVSHCLNSLSE
FMDNMSFLDALLTDVREQNKYGRNDFSWTNGKVTSGLCDEFSLESNDGWT
SQSSGELKAAAEALSFTKCSSAISKALETLNSCKKLGRDPTNDLTFYVSQ
KRNNVYFSQSAANLDNAWKRISVIKSVFSSRSLLYVGNRQASIIEYLPTL
RNICKTEKLKEQGKSKRRFLHYFEGIHLDIPKETVNTLAADFP

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

8ui8 Chain A Residue 2001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8ui8 Cryo-EM map of human clmap-clamp loader ATAD5-RFC-two PCNAs complex in intermediate state 3
Resolution	3.1 Å
Binding residue (original residue number in PDB)	T1139 E1305
Binding residue (residue number reindexed from 1)	T178 E244
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:8ui8, PDBe:8ui8, PDBj:8ui8
PDBsum	8ui8
PubMed	38871854
UniProt	Q96QE3\|ATAD5_HUMAN ATPase family AAA domain-containing protein 5 (Gene Name=ATAD5)

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