Structure of PDB 8ufj Chain A Binding Site BS01

Receptor Information
>8ufj Chain A (length=443) Species: 192952 (Methanosarcina mazei Go1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKCTTKEDVLEAVKERDVKFIRTQFTDTLGIIKSWAIPAEQLEEAFENGV
MFDGSSIQGFTRIEESDMKLALDPSTFRILPWRPATGAVARILGDVYLPD
GNPFKGDPRYVLKTAIKEAEKMGFSMNVGPELEFFLFKLDANGNPTTELT
DQGGYFDFAPLDLGQDVRRDIDYALEHMGFQIEASHHEVAPSQHEIDFRF
GDVLCTADNVVTFKYVVKSIAYHKGYYASFMPKPLFGVNGSGMHSNQSLF
KDGKNVFYDPDTPTKLSQDAMYYIGGLLKHIREFTAVTNPVVNSYKRLVP
GYEAPVYISWSAQNRSSLIRIPATRGNGTRIELRCPDPACNPYLAFALML
RAGLEGIKNKIDPGEPTNVNIFHLSDKEREERGIRSLPADLKEAIDEMKG
SKFVKEALGEHVFSHYLCAKEMEWDEYKAVVHPWELSRYLSML
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8ufj Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8ufj M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation.
Resolution2.45 Å
Binding residue
(original residue number in PDB)		E137 E192 E199
Binding residue
(residue number reindexed from 1)		E133 E188 E195
Annotation score1
Enzymatic activity
Enzyme Commision number 6.3.1.2: glutamine synthetase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004356 glutamine synthetase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006542 glutamine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ufj, PDBe:8ufj, PDBj:8ufj
PDBsum8ufj
PubMed37968329
UniProtQ8PY99|GLNA1_METMA Glutamine synthetase (Gene Name=glnA1)

[Back to BioLiP]