Structure of PDB 8uf4 Chain A Binding Site BS01

Receptor Information
>8uf4 Chain A (length=160) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GEPNQRPELKNHIDRVDAWVGTYFEVKIPSDTFYDHEDTTTDKLKLTLKL
QQLVGEKSWVQFNSNSQLMYGLPDSSHVGKHEYFMHATDKGGLSAVDAFE
IHVHRRPQGDRAPARFKAKFVGDPALVLNDIHKKIALVKKLAFAFGDRNC
STITLQNITR
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8uf4 Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8uf4 Structural and Functional Analysis of Dystroglycan Cell Surface Cleavage Reveals a Novel Regulation Mechanism
Resolution2.43 Å
Binding residue
(original residue number in PDB)		N494 Q495 D525 E527 D581
Binding residue
(residue number reindexed from 1)		N4 Q5 D35 E37 D89
Annotation score4
External links
PDB RCSB:8uf4, PDBe:8uf4, PDBj:8uf4
PDBsum8uf4
PubMed
UniProtQ14118|DAG1_HUMAN Dystroglycan 1 (Gene Name=DAG1)

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