Structure of PDB 8u9r Chain A Binding Site BS01

Receptor Information

>8u9r Chain A (length=1396) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGG
LNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKV
CECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDV
PSRGCGNTQPTIRKDGLKLVGSWKELRVLSTEEILNIFKHISVKDFTSLG
FNEVFSRPEWMILTCLPVPPPPVRPSISFQRGEDDLTFKLADILKANISL
ETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSPVKSIRAR
LKGKEGRRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEV
VTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYG
WKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYN
ADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLC
GIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILS
VAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGL
IHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREI
TETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKA
GRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGF
VDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAV
KTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIE
KQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLL
DEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPS
DLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATR
RVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQM
TLNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQE
QAKLIRSAIEHTTLKSVTIASEIYYDPTVIPEDEEIIQLQQSPWLLRLEL
DRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVEEDH
MLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLET
DGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIAS
DGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEI
LFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYM

Ligand information

>8u9r Chain R (length=10) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

aucgagaggg

..........

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8u9r Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser.
Resolution	3.34 Å
Binding residue (original residue number in PDB)	P448 D483 D485
Binding residue (residue number reindexed from 1)	P419 D454 D456

External links

PDB	RCSB:8u9r, PDBe:8u9r, PDBj:8u9r
PDBsum	8u9r
PubMed	39190355
UniProt	P04050\|RPB1_YEAST DNA-directed RNA polymerase II subunit RPB1 (Gene Name=RPO21)

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