Structure of PDB 8u9j Chain A Binding Site BS01

Receptor Information
>8u9j Chain A (length=242) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DNMASLIQRIARQASLTFREAPMQPGFPENLSKLKSLLTQLRAEDLNIAP
RKATLQPLPPNLPPVTYMHIYETDGFSLGVFLLKSGTSIPLHDHPGMHGM
LKVLYGTVRISCMDKLDAGGGQRPRALPPEQQFEPPLQPREREAVRPGVL
RSRAEYTEASGPCILTPHRDNLHQIDAVEGPAAFLDILAPPYDPDDGRDC
HYYRVLEPVASDLPREVWLLETPQADDFWCEGEPYPGPKVFP
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain8u9j Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8u9j Cobalt(II)-Substituted Cysteamine Dioxygenase Oxygenation Proceeds through a Cobalt(III)-Superoxo Complex.
Resolution2.02 Å
Binding residue
(original residue number in PDB)		H112 H114 H193
Binding residue
(residue number reindexed from 1)		H92 H94 H173
Annotation score1
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0046872 metal ion binding
GO:0047800 cysteamine dioxygenase activity
GO:0051213 dioxygenase activity
Biological Process
GO:0071456 cellular response to hypoxia
Cellular Component
GO:0005739 mitochondrion
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8u9j, PDBe:8u9j, PDBj:8u9j
PDBsum8u9j
PubMed38941563
UniProtQ96SZ5|AEDO_HUMAN 2-aminoethanethiol dioxygenase (Gene Name=ADO)

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