Structure of PDB 8u2m Chain A Binding Site BS01

Receptor Information
>8u2m Chain A (length=380) Species: 2094022 (Micromonospora sp. MW-13) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YDPLAPSVIADPYPFYRKLRETNTVHWHEFLDSWVVTGYAECRQVLGDTT
NFGSDFRRIDVEIPDTQLSVQSLDPPEHGAIRHLLVSALHEQPLSTVRQQ
FAAIAAQHLAELSGQPGTVDLVSRFARPVALRTITAFLGVPPPDGAGFEQ
WSNAIVRSMDAGIEPARAEPGNQARAELSRLVTHWLAEADERGFVGAARR
AARAQDVPAAVLANSLRAVLHAGYESVSRLLGGVLARLVRHPELLAGPAT
RDADEALVDELIRLDGPVQADARVCVRDQPVGAQLVRRGDVLVLFIAAAN
RDPAVFPDPDAVRLTRRRGLHLAFGRGAHACLGAGLATLQLREVLGALRA
GGLRLAPAGPAAYEPTATLRGLAELPVSVR
Ligand information
Receptor-Ligand Complex Structure
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PDB8u2m Structural Insights into a Side Chain Cross-Linking Biarylitide P450 from RiPP Biosynthesis
Resolution1.79 Å
Binding residue
(original residue number in PDB)		Q84 M172 R188 R230 H234 A235 V281 A283 A285 T381 L382
Binding residue
(residue number reindexed from 1)		Q71 M159 R175 R217 H221 A222 V268 A270 A272 T368 L369
Enzymatic activity
Enzyme Commision number 1.14.-.-
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0008395 steroid hydroxylase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0036199 cholest-4-en-3-one 26-monooxygenase activity
GO:0046872 metal ion binding
Biological Process
GO:0006707 cholesterol catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8u2m, PDBe:8u2m, PDBj:8u2m
PDBsum8u2m
PubMed
UniProtA0A3E2YLT4

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