Structure of PDB 8tyh Chain A Binding Site BS01

Receptor Information

>8tyh Chain A (length=333) Species: 126793 (Plasmodium vivax Sal-1)

ENVFLIPLKHLRDSQFVGTLLVGVPPQEIHPIFDTGSTNLWVVTTDCEEE
SCKKVKRYNPYKSKTFRRSFIGKNLHIVFGSGSISGSIGKETFVLGDHTV
RNQTFGLVESESDNIFDYIDFEGIVGLGFPEMLSAGKVSFFDNLLSQNKN
LSPQFSFYISPEDNTSTFLVGGVSKSFYEGSIYMLPVVKEYYWEVELDGI
YVGEKKICCEEKSYAIFDTGTSYNTMPSAQMKGFFDVVPSAPCTEENYQE
VLKNYPVIKYLFGDLVIELLPEEYMILNEESCIPAYMQIDVPSEKNHAYL
LGSIAFMRHYYTVFVRGAGGQPSMVGVAKARAA

Ligand information

• Ligand ID: TEW
• InChI: InChI=1S/O6Te.H2O.17O.6W/c1-7(2,3,4,5)6;;;;;;;;;;;;;;;;;;;;;;;;/h;1H2;;;;;;;;;;;;;;;;;;;;;;;/q;;;;;;;;;;;;;6*-1;;;;;;+1/p-1
• InChIKey: JDLYBIMRCSJRQJ-UHFFFAOYSA-M
• SMILES:
  OpenEye OEToolkits 1.7.6: [O-]=[W]123(O[W]45(=O)(O1[Te]6789O2[W]1(=O)(O3)(O6[W]2(=O)(O1)(O7[W]1(=O)(O2)(O8[W](=O)(O94)(O5)(O1)[O-])[O-])[O-])[O-])[O-])[O]
• Formula: O24 Te W6
• Name: 6-tungstotellurate(VI)
• PDB chain: 8tyh Chain A Residue 702

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8tyh Plasmodium vivax PMX
• Resolution: 1.83 Å
• Binding residue (original residue number in PDB): S266 F267 K270 K287 T301 G339 K340
• Binding residue (residue number reindexed from 1): S69 F70 K73 K90 T104 G136 K137
• Annotation score: 1

External links

• PDB: RCSB:8tyh, PDBe:8tyh, PDBj:8tyh
• PDBsum: 8tyh
• UniProt: A5KAC3