Structure of PDB 8ttu Chain A Binding Site BS01

Receptor Information
>8ttu Chain A (length=256) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFE
VISHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEEEILLND
NDLAVTYFFHQAVDDVKKGYIKAEEKSYQLQKLYEQRKMVMYLNMLRTCE
GYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWD
EMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELK
WRKEEY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ttu Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex.
Resolution2.36 Å
Binding residue
(original residue number in PDB)		D435 S436 R437 R438 L453 Q465 I467 R498
Binding residue
(residue number reindexed from 1)		D163 S164 R165 R166 L181 Q193 I195 R226
External links
PDB RCSB:8ttu, PDBe:8ttu, PDBj:8ttu
PDBsum8ttu
PubMed39116126
UniProtQ96L92|SNX27_HUMAN Sorting nexin-27 (Gene Name=SNX27)

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