Structure of PDB 8ttg Chain A Binding Site BS01

Receptor Information
>8ttg Chain A (length=374) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNKQIFVLYFNIFLIFLGIGLVIPVLPVYLKDLGLTGSDLGLLVAAFALS
QMIISPFGGTLADKLGKKLIICIGLILFSVSEFMFAVGHNFSVLMLSRVI
GGMSAGMVMPGVTGLIADISPSHQKAKNFGYMSAIINSGFILGPGIGGFM
AEVSHRMPFYFAGALGILAFIMSIVLIHDPPQLLTKINWKVFITPVILTL
VLSFGLSAFQTLYSLYTADKVNYSPKDISIAITGGGIFGALFQIYFFDKF
MKYFSELTFIAWSLLYSVVVLILLVFANDYWSIMLISFVVFIGFDMIRPA
ITNYFSNIAGERQGFAGGLNSTFTSMGNFIGPLIAGALFDVHIEAPIYMA
IGVSLAGVVIVLIEKQHRAKLKEQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ttg NorA single mutant - E222Q at pH 7.5
Resolution3.35 Å
Binding residue
(original residue number in PDB)		G59 T60 D63 P110 T113 G114 D118 L195 L196 F327 G330 L331 T334
Binding residue
(residue number reindexed from 1)		G59 T60 D63 P110 T113 G114 D118 L183 L184 F315 G318 L319 T322
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0022857 transmembrane transporter activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ttg, PDBe:8ttg, PDBj:8ttg
PDBsum8ttg
PubMed38802368
UniProtP0A0J7|NORA_STAAU Quinolone resistance protein NorA (Gene Name=norA)

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