Structure of PDB 8tl0 Chain A Binding Site BS01

Receptor Information

>8tl0 Chain A (length=478) Species: 80816 (Haliangium ochraceum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

IQCILVLDLSIDNAITACSVTPHLPRAARRVELHLNDFGAERAPYGGASD
RRTWRCWMQAVDAMLADARAQLGAEVEFTHYYLAGRAALPVFAYLGLRLG
KQANITTVNRRDDGCWDVVPCQRPPSARFFDEVRGLDTDERSSESGMVAV
WVSTQRDVDRGLLRAFARARGDRDLAGIVSLRARPAAGDDTGDMRLLEGA
DGPDAARELVNCFRSIPNQYPRSSGLMVFVSGPVTLAAMVGRAINPRIHG
PVWWPYFRGGEYEPALEYPWPLISGPPRILIATANAPEGENPTLDVEAEL
KHLEEALAEPRKRKLCEVQRCPAATVSDITSALRSFKPHILHFIGHGTAL
GVYLRSAEHDGAQFVRGEDFQQMIATSLRQKDREMHLVVLNACCTHELAK
ALTEQVSCTIGTDIEVYDSASIHFAARFYDHLVHGTSVHYAFNAAVDECR
AHSTSGQEVFCLHPAAPPVRADELVFFS

Ligand information

>8tl0 Chain E (length=3) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

aaa

...

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8tl0 Type III-B CRISPR-Cas cascade of proteolytic cleavages.
Resolution	3.1 Å
Binding residue (original residue number in PDB)	Y65 R106 A107 N129 D132 Q184 M223 L226 S260 G261 P262 V263 F286 Y291
Binding residue (residue number reindexed from 1)	Y45 R86 A87 N109 D112 Q155 M194 L197 S231 G232 P233 V234 F257 Y262

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:8tl0, PDBe:8tl0, PDBj:8tl0
PDBsum	8tl0
PubMed	38301007
UniProt	D0LTI2

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