Structure of PDB 8th7 Chain A Binding Site BS01
Receptor Information
>8th7 Chain A (length=134) Species:
9606
(Homo sapiens) [
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EKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDGKPADAV
YGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQAL
RRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFG
Ligand information
>8th7 Chain C (length=18) Species:
9606
(Homo sapiens) [
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LMAQMQGPYNFIQDSMLD
Receptor-Ligand Complex Structure
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PDB
8th7
Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication.
Resolution
2.88 Å
Binding residue
(original residue number in PDB)
L10 V11 E14 F15 R17 Q18 Q25 H31 R32 F33 Q58 K59 N122 K123 F124 Y125
Binding residue
(residue number reindexed from 1)
L7 V8 E11 F12 R14 Q15 Q22 H28 R29 F30 Q53 K54 N117 K118 F119 Y120
Enzymatic activity
Enzyme Commision number
3.6.4.12
: DNA helicase.
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:8th7
,
PDBe:8th7
,
PDBj:8th7
PDBsum
8th7
PubMed
38492217
UniProt
Q13283
|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (Gene Name=G3BP1)
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