Structure of PDB 8th6 Chain A Binding Site BS01
Receptor Information
>8th6 Chain A (length=138) Species:
9606
(Homo sapiens) [
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MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGK
PADAVYGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSN
NNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVF
Ligand information
>8th6 Chain H (length=18) Species:
9606
(Homo sapiens) [
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PQYIFGDFSPDEFNQFFV
Receptor-Ligand Complex Structure
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PDB
8th6
Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication.
Resolution
2.34 Å
Binding residue
(original residue number in PDB)
V11 F15 Q18 L22 R32 F33 N122 K123 F124
Binding residue
(residue number reindexed from 1)
V11 F15 Q18 L22 R32 F33 N122 K123 F124
Enzymatic activity
Enzyme Commision number
3.6.4.12
: DNA helicase.
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:8th6
,
PDBe:8th6
,
PDBj:8th6
PDBsum
8th6
PubMed
38492217
UniProt
Q13283
|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (Gene Name=G3BP1)
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