Structure of PDB 8th5 Chain A Binding Site BS01
Receptor Information
>8th5 Chain A (length=123) Species:
9606
(Homo sapiens) [
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KPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHPADAVYGQKEIH
RKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTF
VLAPEGSVANKFYVHNDIFRYQD
Ligand information
>8th5 Chain K (length=9) Species:
2697049
(Severe acute respiratory syndrome coronavirus 2) [
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ALRITFGGP
Receptor-Ligand Complex Structure
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PDB
8th5
Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication.
Resolution
2.62 Å
Binding residue
(original residue number in PDB)
F15 R32 N122 K123 F124 Y125
Binding residue
(residue number reindexed from 1)
F11 R28 N110 K111 F112 Y113
Enzymatic activity
Enzyme Commision number
3.6.4.12
: DNA helicase.
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:8th5
,
PDBe:8th5
,
PDBj:8th5
PDBsum
8th5
PubMed
38492217
UniProt
Q13283
|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (Gene Name=G3BP1)
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