Structure of PDB 8tcc Chain A Binding Site BS01

Receptor Information
>8tcc Chain A (length=232) Species: 28450 (Burkholderia pseudomallei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QMPIQRVGVRAVRHPLTVRTQATVGTWNLDVHLPADQKGTHMSRFVALLE
ERGGPLTADAFRTMLATMLEKLEARAGRIEVSFPYFVNKTAPVSGVSLLD
YEVTLTGDVRDGLTRVFAKVLVPVTSLCPCSKKISQHNQRSHVTIDAELA
ADVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDV
ARRLDDERIVAYVLEAENFEHNHSAYALIERD
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain8tcc Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8tcc Combatting melioidosis with chemical synthetic lethality
Resolution3.1 Å
Binding residue
(original residue number in PDB)		C154 H166
Binding residue
(residue number reindexed from 1)		C128 H137
Annotation score1
Gene Ontology
Molecular Function
GO:0003933 GTP cyclohydrolase activity
GO:0003934 GTP cyclohydrolase I activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0046654 tetrahydrofolate biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8tcc, PDBe:8tcc, PDBj:8tcc
PDBsum8tcc
PubMed
UniProtA0A069BB45

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