Structure of PDB 8t7p Chain A Binding Site BS01

Receptor Information
>8t7p Chain A (length=884) Species: 5833 (Plasmodium falciparum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKIHYRKDYKPSGFIINQVTLNINIHDQETIVRSVLDMDISKHNVGEDLV
FDGVGLKINEISINNKKLVEGEEYTYDNEFLTIFSKFVPKSKFAFSSEVI
IHPETNYALTGLYKSKNIIVSQCEATGFRRITFFIDRPDMMAKYDVTVTA
DKEKYPVLLSNGDKVNEFEIPGGRHGARFNDPPLKPCYLFAVVAGDLKHL
SATYITKYTKKKVELYVFSEEKYVSKLQWALECLKKSMAFDEDYFGLEYD
LSRLNLVAVSDFNVGASENKGLNIFNANSLLASKKNSIDFSYARILTVVG
HEYFHQYTGNRVLRDWFQLTLKEGLTVHRENLFSEEMTKTVTTRLSHVDL
LRSVQFLEDSSPLSHPIRPESYVSMENFYTTTVYDKGSEVMRMYLTILGE
EYYKKGFDIYIKKNATCEDFNYAMEQAYKMKKADNSANLNQYLLWFSQSG
TPHVSFKYNYDAEKKQYSIHVNQYTKPDENQKEKKPLFIPISVGLINPEN
GKEMISQTTLELTKESDTFVFNNIAVKPIPSLFRGFSAPVYIEDQLTDEE
RILLLKYDSDAFVRYNSCTNIYMKQILMNYNEFLKAKNEKLESFQLTPVN
AQFIDAIKYLLEDPHADAGFKSYIVSLPQDRYIINFVSNLDTDVLADTKE
YIYKQIGDKLNDVYYKMFKSLEAKADDLTYFNDESHVDFDQMNMRTLRNT
LLSLLSKAQYPNILNEIIEHSKSPYPSNWLTSLSVSAYFDKYFELYDKTY
KLSKDDELLLQEWLKTVSRSDRKDIYEILKKLENEVLKDSKNPNDIRAVY
LPFTNNLRRFHDISGKGYKLIAEVITKTDKFNPMVATQLCEPFKLWNKLD
TKRQELMLNEMNTMLQEPQISNNLKEYLLRLTNK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8t7p Chain A Residue 1101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8t7p Conformational dynamics of the Plasmodium falciparum M1 aminopeptidase.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		H496 H500 E519
Binding residue
(residue number reindexed from 1)		H301 H305 E323
Annotation score4
External links
PDB RCSB:8t7p, PDBe:8t7p, PDBj:8t7p
PDBsum8t7p
PubMed
UniProtO96935|AMPN_PLAF7 Aminopeptidase N (Gene Name=M1AAP)

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