Structure of PDB 8t1u Chain A Binding Site BS01

Receptor Information
>8t1u Chain A (length=353) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EPIRLPNPMIGFGVPNEPGLITHRSLPELARGPPFFYYENVALTPKGVWE
TISRHLFEIPPEFVDSKYFCVAARKRGYIHNLPINNRFQIQPPPKYTIHD
AFPLSKRWWPEWDKRTKLNCILTCTGSAQLTNRIRVALEPYNEEPEPPKH
VQRYVIDQCKKWNLVWVGKNKAAPLEPDEMESILGFPKNHTRGGGMSRTE
RFKSLGNSFQVDTVAYHLSVLKPIFPHGINVLSLFTGIGGGEVALHRLQI
KMKLVVSVEISKVNRNILKDFWEQTNQTGELIEFSDIQHLTNDTIEGLME
KYGGFDLVIGGSPCNNLAGGNRVSRVGLEGDQSSLFFEYCRILEVVRARM
RGS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8t1u DNA conformational dynamics in the context-dependent non-CG CHH methylation by plant methyltransferase DRM2.
Resolution2.91 Å
Binding residue
(original residue number in PDB)
L278 P318 K319 S400 A401 Q402 S470 T472 G592 N594 R595 R598
Binding residue
(residue number reindexed from 1)
L5 P45 K46 S127 A128 Q129 S197 T199 G319 N321 R322 R325
Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:8t1u, PDBe:8t1u, PDBj:8t1u
PDBsum8t1u
PubMed37926286
UniProtQ9M548|DRM2_ARATH DNA (cytosine-5)-methyltransferase DRM2 (Gene Name=DRM2)

[Back to BioLiP]