Structure of PDB 8sxg Chain A Binding Site BS01

Receptor Information
>8sxg Chain A (length=366) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAPLPLDELRTFAEVLDRVKAAYVEPVDDKTLLENAIKGMLSNLDPHSAY
LGPEDFAELQESTSGEFGGLGIEVGSEDGFIKVVSPIDDTPAARAGIQPG
DLIVQIDGKPTKGQSMTEAVDSMRGKAGSPITLTIVRDGGRPFDVELKRA
IIKVKSVKSQVLEPGYAYLRITQFQVNTGEEVVKALNQLRKDNKGRLKGL
VLDLRNNPGGVLQSAVEVADAFLTKGLIVYTKGRIANSELRFSADPADPS
DKVPLVVLINGGSAAAAEIVAGALQDQKRAILMGTDSFGKGSVQTVLPLN
NDRALKLTTALYYTPNGRSIQAQGIVPDIEVGRAKVTQESERPQDSDYQL
SQALSLLKGLSVTRGN
Ligand information
Receptor-Ligand Complex Structure
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PDB8sxg P. aeruginosa CtpA protease adopts a novel activation mechanism to initiate the proteolytic process
Resolution4.14 Å
Binding residue
(original residue number in PDB)		G247 A302 K327 Q331
Binding residue
(residue number reindexed from 1)		G210 A265 K290 Q294
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0007165 signal transduction
GO:0030254 protein secretion by the type III secretion system
GO:0042546 cell wall biogenesis
GO:0043163 cell envelope organization
Cellular Component
GO:0005886 plasma membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0030313 cell envelope
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8sxg, PDBe:8sxg, PDBj:8sxg
PDBsum8sxg
PubMed38467832
UniProtQ9HU50

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