Structure of PDB 8swb Chain A Binding Site BS01

Receptor Information
>8swb Chain A (length=149) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDFVVVYTDGCCSSNGRRRPRAGIGVYWGPGHPLNVGIRLPGRQTNQRAE
IHAACKAIEQAKTQNINKLVLYTNSMFTINGITNWVQGWKKNGWKTSAGK
EVINKEDFVALERLTQGMDIQWMHVPGHSGFIGNEEADRLAREGAKQSE
Ligand information
>8swb Chain B (length=20) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggcgagugggugagugagg
....................
Receptor-Ligand Complex Structure
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PDB8swb Crystal structure of RNase H/RNA/PS-ASO complex at an atomic level
Resolution2.0 Å
Binding residue
(original residue number in PDB)		C147 C148 S150 N151 R153 N182 Q183 E186 N210 M212 H260
Binding residue
(residue number reindexed from 1)		C11 C12 S14 N15 R17 N46 Q47 E50 N74 M76 H124
Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
External links
PDB RCSB:8swb, PDBe:8swb, PDBj:8swb
PDBsum8swb
PubMed
UniProtO60930|RNH1_HUMAN Ribonuclease H1 (Gene Name=RNASEH1)

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