Structure of PDB 8suv Chain A Binding Site BS01
Receptor Information
>8suv Chain A (length=128) Species:
9606
(Homo sapiens) [
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SPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLK
MQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYS
LAKEQRLNFGDDIPSALRIAKKKRWNSI
Ligand information
>8suv Chain F (length=10) Species:
9606
(Homo sapiens) [
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LPKTPIFRPD
Receptor-Ligand Complex Structure
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PDB
8suv
Interaction with the membrane-anchored protein CHIC2 constrains the ubiquitin ligase activity of CHIP
Resolution
1.63 Å
Binding residue
(original residue number in PDB)
K30 N34 F37 Y49 N65 L68 K95 F98 F99 Q102 R128 N130 F131 D134 I135
Binding residue
(residue number reindexed from 1)
K8 N12 F15 Y27 N43 L46 K73 F76 F77 Q80 R106 N108 F109 D112 I113
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:8suv
,
PDBe:8suv
,
PDBj:8suv
PDBsum
8suv
PubMed
UniProt
Q9UNE7
|CHIP_HUMAN E3 ubiquitin-protein ligase CHIP (Gene Name=STUB1)
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