Structure of PDB 8soq Chain A Binding Site BS01

Receptor Information
>8soq Chain A (length=203) Species: 220668 (Lactiplantibacillus plantarum WCFS1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RRNGFPEVIYGAGKTATQIVGIVQALSQQTLPILTTRLSAEKFAALQPAL
PTAVYHATAQCMTVGEQPAPKTPGYIAVVTAGTADQPVAEEAAVTAETFG
NRVERVYDVGVAGIHRLFAKLDVIRGARVVIVIAGMEGALASVVGGLVDK
PVIAVPTSVGYGTSFQGMTALLTMLNSCASGITVVNIDNGFGAAYSASMV
NQM
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8soq Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8soq Structure of the LarB-Substrate Complex and Identification of a Reaction Intermediate during Nickel-Pincer Nucleotide Cofactor Biosynthesis.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
G188 V191
Binding residue
(residue number reindexed from 1)
G145 V148
Annotation score1
Enzymatic activity
Enzyme Commision number 2.5.1.143: pyridinium-3,5-biscarboxylic acid mononucleotide synthase.
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006189 'de novo' IMP biosynthetic process
Cellular Component
GO:0005886 plasma membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8soq, PDBe:8soq, PDBj:8soq
PDBsum8soq
PubMed37831946
UniProtF9UST0|LARB_LACPL Pyridinium-3,5-biscarboxylic acid mononucleotide synthase (Gene Name=larB)

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