Structure of PDB 8sky Chain A Binding Site BS01

Receptor Information
>8sky Chain A (length=302) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKFATGELYNRMFVGLIIDDEKIMDLQKAEKKLFELETIPGSLIECIAEG
DKFVAHARQLAEWAKKPNDELGSFMYSLSEVKLHAPIPKPSKNIICIGKN
YRDHAIEMGSEADIPEHPMVFTKSPVTVTGHGDIVKSHEEVTSQLDYEGE
LAVVIGKSGTRISKEDAYDHVFGYTIVNDITARDLQKRHKQFFIGKSLDT
TCPMGPVLVHKSSIQEPERLKVETRVNGELRQSGSASDMIFSIPELIETL
SKGMTLEAGDIIATGTPSGVGKGFTPPKFLRSGDKIDITIDPIGTLSNQI
GL
Ligand information
Ligand IDOXL
InChIInChI=1S/C2H2O4/c3-1(4)2(5)6/h(H,3,4)(H,5,6)/p-2
InChIKeyMUBZPKHOEPUJKR-UHFFFAOYSA-L
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341		[O-]C(=O)C([O-])=O
OpenEye OEToolkits 1.5.0C(=O)(C(=O)[O-])[O-]
FormulaC2 O4
NameOXALATE ION
ChEMBL
DrugBank
ZINC
PDB chain8sky Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8sky Bacillus subtilis YisK possesses oxaloacetate decarboxylase activity and exhibits Mbl-dependent localization
Resolution2.4 Å
Binding residue
(original residue number in PDB)		I97 G98 K99 F121 E148 E150 K196 G265 T266
Binding residue
(residue number reindexed from 1)		I97 G98 K99 F121 E148 E150 K196 G265 T266
Annotation score2
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008948 oxaloacetate decarboxylase activity
GO:0016829 lyase activity
GO:0016853 isomerase activity
GO:0018773 acetylpyruvate hydrolase activity
GO:0046872 metal ion binding
GO:0050163 oxaloacetate tautomerase activity
Biological Process
GO:0006107 oxaloacetate metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8sky, PDBe:8sky, PDBj:8sky
PDBsum8sky
PubMed38047707
UniProtO06724|YISK_BACSU Oxaloacetate tautomerase YisK (Gene Name=yisK)

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