Structure of PDB 8rn3 Chain A Binding Site BS01

Receptor Information

>8rn3 Chain A (length=706) Species: 1601067 (Influenza B virus (B/Memphis/13/2003)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MDTFITRNFQTTIIQKAKNTMAEFSEDPELQPAMLFNICVHLEVCYVISD
MNFLDEEGKAYNLRPQYEVIEGMPRTIAWMVQRSLAQEHGIETPKYLADL
FDYKTKRFIEVGITKGLADDYFWKKKEKLGNSMELMIFSYNQDYSLSNES
SLDEEGKGRVLSRLTELQAELSLKNLWQVLIGEEDVEKGIDFKLGQTISR
LRDISVPAGFSNFEGMRSYIDNIDPKGAIERNLARMSPLVSVTPKKLTWE
DLRPIGPHIYNHELPEVPYNAFLLMSDELGLANMTEGKSKKPKTLAKECL
EKYSTLRDQTDPILIMKSEKANENFLWKLWRDCVNTISNEEMSNELQKTN
YAKWATGDGLTYQKIMKEVAIDDETMCQEEPKIPNKCRVAAWVQTEMNLL
STLTSKRALDLPEIGPDVAPVEHVGSERRKYFVNEINYCKASTVMMKYVL
FHTSLLNESNASMGKYKVIPITNRVVNEKGESFDMLYGLAVKGQSHLRGD
TDVVTVVTFEFSSTDPRVDSGKWPKYTVFRIGSLFVSGREKSVYLYCRVN
GTNKIQMKWGMEARRCLLQSMQQMEAIVEQESSIQGYDMTKACFKGDRVN
SPKTFSIGTQEGKLVKGSFGKALRVIFTKCLMHYVFGNAQLEGFSAESRR
LLLLIQALKDRKGPWVFDLEGMYSGIEECISNNPWVIQSAYWFNEWLGFE
KEGSKV

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

8rn3 Chain A Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	8rn3 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase.
Resolution	2.78 Å
Binding residue (original residue number in PDB)	D109 E120
Binding residue (residue number reindexed from 1)	D99 E110
Annotation score	4

External links

PDB	RCSB:8rn3, PDBe:8rn3, PDBj:8rn3
PDBsum	8rn3
PubMed	39160148
UniProt	Q5V8Z9

[Back to BioLiP]