Structure of PDB 8rdr Chain A Binding Site BS01

Receptor Information
>8rdr Chain A (length=108) Species: 55518 (Magnetospirillum gryphiswaldense) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APGASIFRCRQCGQTISRRDWLLPMGGDHEHVVFNPAGMIFRVWCFSLAQ
GLRLIGAPSGEFSWFKGYDWTIALCGQCGSHLGWHYEGGSQPQTFFGLIK
DRLAEGPA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8rdr Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8rdr Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode.
Resolution1.58 Å
Binding residue
(original residue number in PDB)		C24 C27 C90 C93
Binding residue
(residue number reindexed from 1)		C9 C12 C75 C78
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8rdr, PDBe:8rdr, PDBj:8rdr
PDBsum8rdr
PubMed38552426
UniProtA4TVL0

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