Structure of PDB 8rcv Chain A Binding Site BS01

Receptor Information
>8rcv Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFITVGYVDDTQFVRFDSDATSPRMAPRAP
WIEQEGPEYWDRETQISKTNTQTYRENLRTALRYYNQSEAGSHIIQRMYG
CDLGPDGRLLRGHNQLAYDGKDYIALNEDLSSWTAADTAAQITQLKWEAA
RVAEQLRAYLEGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>8rcv Chain C (length=10) Species: 2697049 (Severe acute respiratory syndrome coronavirus 2) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SVLNDIFSRL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8rcv The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific.
Resolution1.65 Å
Binding residue
(original residue number in PDB)		Y7 R62 E63 I66 E76 N77 Y84 R97 Y99 T143 K146 W147 Q155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		Y7 R62 E63 I66 E76 N77 Y84 R97 Y99 T143 K146 W147 Q155 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation

View graph for
Biological Process
External links
PDB RCSB:8rcv, PDBe:8rcv, PDBj:8rcv
PDBsum8rcv
PubMed38742159
UniProtC5IYE8

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