Structure of PDB 8rbu Chain A Binding Site BS01

Receptor Information
>8rbu Chain A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYG
CDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HAAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>8rbu Chain C (length=10) Species: 2697049 (Severe acute respiratory syndrome coronavirus 2) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SVLNDILARL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8rbu The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		Y7 Y9 E63 N66 V67 A69 Q70 T73 D74 D77 T80 I95 Y99 D116 T143 K146 W147 A152 Q155 Q156 Y159 R163 W167 Y171
Binding residue
(residue number reindexed from 1)		Y7 Y9 E63 N66 V67 A69 Q70 T73 D74 D77 T80 I95 Y99 D116 T143 K146 W147 A152 Q155 Q156 Y159 R163 W167 Y171
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation

View graph for
Biological Process
External links
PDB RCSB:8rbu, PDBe:8rbu, PDBj:8rbu
PDBsum8rbu
PubMed38742159
UniProtQ5S3G3

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