Structure of PDB 8r34 Chain A Binding Site BS01

Receptor Information
>8r34 Chain A (length=485) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKLDLEYYRWPVALPKLFFTKKAYKIYFIILVTGLLLGIKTFNDAAQHRC
MALVECVAFLWASEAIPLHITAFLVPLLVVLFKVLKTSDGAIMSAASASS
EILAAMWSSTIMILLAGFTLGEVLAQYNIAKVLASWLLAFAGCKPRNVLL
MAMCVVFFLSMWISNVAAPVLTYSLLSPLLDAMDADSPFAQALVLGVALA
ANIGGMSSPISSPQNIISMSYLKPYGIGWGQFFAVALPSGILAMLLVWIL
LFTTFKMNKTKLEKFKPIKTKFTVKQYYIITVTVATILLWCVESQIEGAF
GSSGQIAIIPIVLFFGTGLLSTQDLNAFPWSIVILAMGGIALGKAVSSSG
LLSTIAKALQKKIENDGVFAILCIFGILMLVVGTFVSHTVSAIIIIPLVQ
EVGDKLGNPKAAPILVFGCALLSSCGMGLASSGFPNVTAISKVDRKGDRY
LSVMTFLTRGVPASILAFLCVITLGYGIMASVVKG
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain8r34 Chain A Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8r34 Complementary structures of the yeast phosphate transporter Pho90 provide insights into its transport mechanism
Resolution2.62 Å
Binding residue
(original residue number in PDB)		N556 G596 Q605 H779 S815
Binding residue
(residue number reindexed from 1)		N165 G205 Q214 H388 S424
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005315 phosphate transmembrane transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0006797 polyphosphate metabolic process
GO:0006817 phosphate ion transport
GO:0055085 transmembrane transport
GO:2000185 regulation of phosphate transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0071944 cell periphery

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8r34, PDBe:8r34, PDBj:8r34
PDBsum8r34
PubMed38688287
UniProtP39535|PHO90_YEAST Low-affinity phosphate transporter PHO90 (Gene Name=PHO90)

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