Structure of PDB 8qto Chain A Binding Site BS01

Receptor Information

>8qto Chain A (length=234) Species: 668 (Aliivibrio fischeri) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

AIHCQDCSISQHCIPFTLNDSELDQLDEIIERKKPIQKGQELFKAGDELK
CLYAIRSGTIKSYTITEQGDEQITAFHLAGDLVGFDAITEAQHPSFAQAL
ETSMVCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILLLSKKNA
EERLAAFLYNLSTRFHQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLG
RFQKTEMLTVKGKYITINDHDALAELAGSAKEIK

Ligand information

InChI=1S/4Fe.4S

LJBDFODJNLIPKO-UHFFFAOYSA-N

SMILES

Software	SMILES
OpenEye OEToolkits 2.0.7	[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385	S1[Fe]S[Fe]1.S2[Fe]S[Fe]2

Formula

Fe4 S4

Name

IRON/SULFUR CLUSTER

ChEMBL

DrugBank

ZINC

PDB chain

8qto Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8qto The crystal structure of the global anaerobic transcriptional regulator FNR explains its extremely fine-tuned monomer-dimer equilibrium.
Resolution	2.4 Å
Binding residue (original residue number in PDB)	C20 C23 I25 C29 P31 R48 R72 C122
Binding residue (residue number reindexed from 1)	C4 C7 I9 C13 P15 R32 R56 C106
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity
GO:0046872	metal ion binding
GO:0051537	2 iron, 2 sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding

	Biological Process
GO:0006355	regulation of DNA-templated transcription

	Cellular Component
GO:0005829	cytosol

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Cellular Component

External links

PDB	RCSB:8qto, PDBe:8qto, PDBj:8qto
PDBsum	8qto
PubMed
UniProt	Q70ET4

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