Structure of PDB 8qns Chain A Binding Site BS01

Receptor Information
>8qns Chain A (length=449) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IRAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPL
SKELWFSDDPNVTKTLQFRQWNGKERSIYFQPPSFYVSAQDLPNIENGGV
AVLTGKKVVHLDVRGNMVKLNDGSQITFEKCLIATGGTPRSLSAIDRAGA
EVKSRTTLFRKIGDFRALEKISREVKSITVIGGGFLGSELACALGRKSQA
SGIEVIQLFPEKGNMGKILPQYLSNWTMEKVKREGVKVMPNAIVQSVGVS
GGRLLIKLKDGRKVETDHIVTAVGLEPNVELAKTGGLEIDSDFGGFRVNA
ELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKP
YWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATEEDYGKGVIFYLR
DKVVVGIVLWNVFNRMPIARKIIKDGEQHEDLNEVAKLFNIHEDLVPRG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8qns Structural characterization of the interaction between apoptosis inducing factor (AIF) and CHCHD4.
Resolution3.206 Å
Binding residue
(original residue number in PDB)		P344 Y346 S499 S500 L501 P502 T503 V504 G505 V506 F507 A508 K509 T511 E557 Y559 K605 H610
Binding residue
(residue number reindexed from 1)		P220 Y222 S375 S376 L377 P378 T379 V380 G381 V382 F383 A384 K385 T387 E389 Y391 K437 H442
Enzymatic activity
Enzyme Commision number 1.6.99.-
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046983 protein dimerization activity

View graph for
Molecular Function
External links
PDB RCSB:8qns, PDBe:8qns, PDBj:8qns
PDBsum8qns
PubMed
UniProtQ9Z0X1|AIFM1_MOUSE Apoptosis-inducing factor 1, mitochondrial (Gene Name=Aifm1)

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