Structure of PDB 8qc0 Chain A Binding Site BS01

Receptor Information
>8qc0 Chain A (length=149) Species: 251229 (Chroococcidiopsis thermalis PCC 7203) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRKIIYLASPYGFSQQQKTLLLPPIVRALEALGIEVWEPFARNFSQADWA
YRVAQADLQDVKNCDGIFAVVNGTPPDEGVMVELGMAIALNKAIFLFRDD
FRRCSDNERYPLNLMLFAGLPEIGWENYYYTSVDEIQSHDKALYKWLTG
Ligand information
Ligand IDRIB
InChIInChI=1S/C5H10O5/c6-1-2-3(7)4(8)5(9)10-2/h2-9H,1H2/t2-,3-,4-,5+/m1/s1
InChIKeyHMFHBZSHGGEWLO-AIHAYLRMSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(O1)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@H]([C@H](O1)O)O)O)O
ACDLabs 10.04OC1C(OC(O)C1O)CO
FormulaC5 H10 O5
Namealpha-D-ribofuranose;
alpha-D-ribose;
D-ribose;
ribose
ChEMBLCHEMBL606078
DrugBank
ZINCZINC000003860714
PDB chain8qc0 Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8qc0 Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase
Resolution2.02 Å
Binding residue
(original residue number in PDB)		F14 D62 G84 E88
Binding residue
(residue number reindexed from 1)		F13 D57 G79 E83
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0046872 metal ion binding
GO:0070694 deoxyribonucleoside 5'-monophosphate N-glycosidase activity
Biological Process
GO:0009159 deoxyribonucleoside monophosphate catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8qc0, PDBe:8qc0, PDBj:8qc0
PDBsum8qc0
PubMed38449528
UniProtK9TVX3

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