Structure of PDB 8q6d Chain A Binding Site BS01

Receptor Information
>8q6d Chain A (length=220) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFT
DGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGK
LGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDA
KVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAI
TVWYFDADERARAKVKYLTG
Ligand information
>8q6d Chain B (length=20) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ELDLETLAPYIPMDGEDFQL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8q6d HIF prolyl hydroxylase 2 in complex with HIF2alpha-CODD
Resolution1.4 Å
Binding residue
(original residue number in PDB)
Q239 L240 V241 S242 R252 W258 D277 R281 N293 G294 R295 Y310 H313 V314 D315 P317 N318 R322 W389 F391 R396 K400
Binding residue
(residue number reindexed from 1)
Q53 L54 V55 S56 R66 W72 D91 R95 N107 G108 R109 Y124 H127 V128 D129 P131 N132 R136 W203 F205 R210 K214
External links
PDB RCSB:8q6d, PDBe:8q6d, PDBj:8q6d
PDBsum8q6d
PubMed
UniProtQ9GZT9|EGLN1_HUMAN Egl nine homolog 1 (Gene Name=EGLN1)

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