Structure of PDB 8q42 Chain A Binding Site BS01

Receptor Information
>8q42 Chain A (length=434) Species: 509193 (Thermoanaerobacter brockii subsp. finnii Ako-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NEKVLVLIVGTNPLPNYVVGSHLKEKYDKFVLIYSEKNDKINQNSTYDYA
KKLKEHLNLNDKCIFLPLSDVSNSEKIINDLREKFPSEDFVEVHLNYTGG
TKTMVVHIYNFLKEKFKNNKIKFEGSYLDARDYKLVYDYSEEAISLKDTI
KIDINTLLSIHLYEDIHFEFYDTYSYKQKFVDSFDKISQEIEKAIKDDKG
EDFVKWLEDPFRKIFKGENKLLEKTAKFKKHIEKLLKDSSPIVKFNEKTP
QFIWDILNAFPEGKKLNDGQKLWIPDDKITNDNLSSRVKDTVEFLNGKWF
EWYVYSQIKSELLDRKLKEGEHFGISLKAQKKDSPYFALDIFLINGYQLI
GISLTTSSTRELCKLKGFEVIHRVRQIGGDESKAILITGMDKSKTEDLQK
DLAYETGSTQKRFVVFGIDDWADIGSKICEEVFK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8q42 Substrate selectivity and catalytic activation of the type III CRISPR-associated ancillary nuclease Can2
Resolution1.97 Å
Binding residue
(original residue number in PDB)		R213 N299 G300 K301 T358 T359 S360
Binding residue
(residue number reindexed from 1)		R212 N296 G297 K298 T355 T356 S357
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8q42, PDBe:8q42, PDBj:8q42
PDBsum8q42
PubMed38033326
UniProtE8URK0

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