Structure of PDB 8pzp Chain A Binding Site BS01

Receptor Information
>8pzp Chain A (length=470) Species: 382835 (Influenza A virus (A/WSN/1933(H1N1))) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSA
FDERRNKYLEEHPSAGKDPKKTGGPIYRRVDGKWRRELILYDKEEIRRIW
RQANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGS
TLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYE
RMCNILKGKFQTAAQRTMVDQVRESRNPGNAEFEDLIFLARSALILRGSV
AHKSCLPACVYGSAVASGYDFEREGYSLVGIDPFRLLQNSQVYSLIRPNE
NPAHKSQLVWMACHSAAFEDLRVSSFIRGTKVVPRGKLSTRGVQIASNEN
METMESSTLELRSRYWAIRTRSGGNTNQQRASSGQISIQPTFSVQRNLPF
DRPTIMAAFTGNTEGRTSDMRTEIIRLMESARPEDVSFQGRGVFELSDEK
ATSPIVPSFDMSNEGSYFFG
Ligand information
Receptor-Ligand Complex Structure
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PDB8pzp Cryo-EM structure of influenza helical nucleocapsid reveals NP-NP and NP-RNA interactions as a model for the genome encapsidation.
Resolution8.7 Å
Binding residue
(original residue number in PDB)		V299 T390 R391 S392 Q398 R461
Binding residue
(residue number reindexed from 1)		V279 T370 R371 S372 Q378 R441
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005198 structural molecule activity
Biological Process
GO:0046718 symbiont entry into host cell
GO:0075732 viral penetration into host nucleus
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8pzp, PDBe:8pzp, PDBj:8pzp
PDBsum8pzp
PubMed38100595
UniProtA0A2Z5UJ33

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