Structure of PDB 8pwm Chain A Binding Site BS01

Receptor Information
>8pwm Chain A (length=238) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRRLSMLPHLADLVSY
SIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSW
SCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAI
CLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLA
DLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pwm Novel Des-C-Ring and Aromatic-D-Ring analogs Acting as Potent Agonists of the Vitamin D Receptor (VDR)
Resolution2.3 Å
Binding residue
(original residue number in PDB)
K274 R280 Q287 I288 K292 P442 L443 E446 V447 E451 V452
Binding residue
(residue number reindexed from 1)
K60 R66 Q73 I74 K78 P228 L229 E232 V233 E237 V238
External links
PDB RCSB:8pwm, PDBe:8pwm, PDBj:8pwm
PDBsum8pwm
PubMed
UniProtQ9PTN2|VDRA_DANRE Vitamin D3 receptor A (Gene Name=vdra)

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