Structure of PDB 8pwd Chain A Binding Site BS01
Receptor Information
>8pwd Chain A (length=237) Species:
7955
(Danio rerio) [
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MLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRRLSMLPHLADLVSY
SIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSW
SCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAI
CLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLA
DLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSE
Ligand information
>8pwd Chain B (length=9) Species:
9606
(Homo sapiens) [
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HKILHRLLQ
Receptor-Ligand Complex Structure
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PDB
8pwd
Novel Des-C-Ring and Aromatic-D-Ring analogs Acting as Potent Agonists of the Vitamin D Receptor (VDR)
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
K274 R280 I288 E446
Binding residue
(residue number reindexed from 1)
K60 R66 I74 E232
External links
PDB
RCSB:8pwd
,
PDBe:8pwd
,
PDBj:8pwd
PDBsum
8pwd
PubMed
UniProt
Q9PTN2
|VDRA_DANRE Vitamin D3 receptor A (Gene Name=vdra)
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