BioLiP

Receptor Information

>8pvv Chain A (length=427) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MMEYKIVENGLTYRIGNGASVPISNTGELIKGLRNYGPYEVPSLKYNQIA
LIHNNQFSSLINQLKSQISSKIDEVWHIHNINISEFIYDSPHFDSIKSQV
DNAIDTGVDGIMLVLPEYNTPLYYKLKSYLINSIPSQFMRYDILSNRNLT
FYVDNLLVQFVSKLGGKPWILNVDPEKGSDIIIGTGATRIDNVNLFCFAM
VFKKDGTMLWNEISPIVTSSEYLTYLKSTIKKVVYGFKKSNPDWDVEKLT
LHVSGKRPKMKDGETKILKETVEELKKQEMVSRDVKYAILHLNETHPFWV
MGDPNNRFHPYEGTKVKLSSKRYLLTLLQPYLKRNGLEMVTPIKPLSVEI
VSDNWTSEEYYHNVHEILDEIYYLSKMNWRGFRSRNLPVTVNYPKLVAGI
IANVNRYGGYPINPEGNRSLQTNPWFL

>8pvv Chain R (length=25) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

aggagggcggagccuauggaaaaac

.........................

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8pvv The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein.
Resolution	2.81 Å
Binding residue (original residue number in PDB)	Y118 N119 T120 Y123 K127 Q137 F138 R140 I143 R147 Y152 N155 Q159 K163 R189 N192 N194 R257 K259 M260 W299 T341 P342 K344 R380 R385 N386
Binding residue (residue number reindexed from 1)	Y118 N119 T120 Y123 K127 Q137 F138 R140 I143 R147 Y152 N155 Q159 K163 R189 N192 N194 R257 K259 M260 W299 T341 P342 K344 R380 R385 N386

Enzyme Commision number

	Molecular Function
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003723	RNA binding
GO:0046872	metal ion binding

PDB	RCSB:8pvv, PDBe:8pvv, PDBj:8pvv
PDBsum	8pvv
PubMed	38197228
UniProt	O28951\|PIWI_ARCFU Piwi protein (Gene Name=AF_1318)

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Structure of PDB 8pvv Chain A Binding Site BS01