Structure of PDB 8pk6 Chain A Binding Site BS01

Receptor Information
>8pk6 Chain A (length=229) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LEMKIFSESHKTVFVVDHCPYMAESSLWTCSVESSMEYCRIMYDIFPFKK
LVNFIVSDSGAHVLNSWTQEDQNLQELMAALAAVGPPNPRADPECCSILH
GLVAAVETLCKITEYQHEARTLLMENAERVGNRGRIICITNAKSDSHVRM
LEDCVQETIHEHNKLAANSDHLMQIQKCELVLIHTYPVGLVSDRSKKELS
PVLTSEVHSVRAGRHLATKLNILVQQHFD
Ligand information
>8pk6 Chain B (length=23) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
EDRLERLQEILRKFLYLEREFRQ
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pk6 Basis of gene-specific transcription regulation by the Integrator complex.
Resolution3.21 Å
Binding residue
(original residue number in PDB)		S101 L103 V107 E111 S150 H151 M154 C158 E161 E165 K168
Binding residue
(residue number reindexed from 1)		S97 L99 V103 E107 S146 H147 M150 C154 E157 E161 K164
External links
PDB RCSB:8pk6, PDBe:8pk6, PDBj:8pk6
PDBsum8pk6
PubMed38906142
UniProtQ9NVM9|INT13_HUMAN Integrator complex subunit 13 (Gene Name=INTS13)

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