Structure of PDB 8pjf Chain A Binding Site BS01

Receptor Information

>8pjf Chain A (length=180) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRF
ASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELRE
PNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYL
PFLPSTEDVYDCRVEHWGLDEPLLKHWEFD

Ligand information

>8pjf Chain C (length=13) Species: 11320 (Influenza A virus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

PKYVKQNTLKLAR

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8pjf A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation.
Resolution	1.48 Å
Binding residue (original residue number in PDB)	Q9 E11 A52 S53 F54 E55 G58 N62 D66 N69 M73
Binding residue (residue number reindexed from 1)	Q8 E10 A51 S52 F53 E54 G57 N61 D65 N68 M72

External links

PDB	RCSB:8pjf, PDBe:8pjf, PDBj:8pjf
PDBsum	8pjf
PubMed	38819988
UniProt	P01903\|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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