Structure of PDB 8pi9 Chain A Binding Site BS01

Receptor Information
>8pi9 Chain A (length=165) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPEEAAHQKAVVETLLQEDPWRVAKMVKSYLQQHNIPQREVVDTTGLNQS
HLSQHLNKGTPMKTQKRAALYTWYVRKQREVAQQFTHARRNRFKWGPASQ
QILFQAYERQKNPSKEERETLVEECNRAECIQRGVSPSQAQGLGSNLVTE
VRVYNWFANRRKEEA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pi9 Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		P129 Q130 R131 Q141 S145 Y265 R272 K273
Binding residue
(residue number reindexed from 1)		P37 Q38 R39 Q49 S53 Y154 R161 K162
External links
PDB RCSB:8pi9, PDBe:8pi9, PDBj:8pi9
PDBsum8pi9
PubMed38855865
UniProtP20823|HNF1A_HUMAN Hepatocyte nuclear factor 1-alpha (Gene Name=HNF1A)

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