Structure of PDB 8phe Chain A Binding Site BS01

Receptor Information
>8phe Chain A (length=551) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AFAKELFLGKIKKKEVFPFPEVSQDELNEINQFLGPVEKFFTEEVDSRKI
DQEGKIPDETLEKLKSLGLFGLQVPEEYGGLGFSNTMYSRLGEIISMDGS
ITVTLAAHQAIGLKGIILAGTEEQKAKYLPKLASGEHIAAFCLTEPASGS
DAASIRSRATLSEDKKHYILNGSKVWITNGGLANIFTVFAKTEVVDSDGS
VKDKITAFIVERDFGGVTNGKPEDKLGIRGSNTCEVHFENTKIPVENILG
EVGDGFKVAMNILNSGRFSMGSVVAGLLKRLIEMTAEYACTRKQFNKRLS
EFGLIQEKFALMAQKAYVMESMTYLTAGMLDQPGFPDCSIEAAMVKVFSS
EAAWQCVSEALQILGGLGYTRDYPYERILRDTRILLIFEGTNEILRMYIA
LTGLQHAGRILTTRIHHGVVHPSLADSANKFEENTYCFGRTVETLLLRFG
KTIMEEQLVLKRVANILINLYGMTAVLSRASRSIRIGLRNHDHEVLLANT
FCVEAYLQNLFSLSQLDKYAPENLDEQIKKVSQQILEKRAYICAHPLDRT
C
Ligand information
Receptor-Ligand Complex Structure
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PDB8phe The assembly of the Mitochondrial Complex I Assembly complex uncovers a redox pathway coordination
Resolution3.1 Å
Binding residue
(original residue number in PDB)		F332 N333
Binding residue
(residue number reindexed from 1)		F295 N296
Enzymatic activity
Enzyme Commision number 1.3.8.-
Gene Ontology
Molecular Function
GO:0003995 acyl-CoA dehydrogenase activity
GO:0004466 long-chain fatty acyl-CoA dehydrogenase activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
GO:0070991 medium-chain fatty acyl-CoA dehydrogenase activity
Biological Process
GO:0001676 long-chain fatty acid metabolic process
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0051791 medium-chain fatty acid metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0030425 dendrite
GO:0031966 mitochondrial membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8phe, PDBe:8phe, PDBj:8phe
PDBsum8phe
PubMed38086790
UniProtQ9H845|ACAD9_HUMAN Complex I assembly factor ACAD9, mitochondrial (Gene Name=ACAD9)

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