Structure of PDB 8pha Chain A Binding Site BS01

Receptor Information
>8pha Chain A (length=450) Species: 98349 (Pleurotus sapidus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PSEGKAQIRALLNLINTSAEQAIAEYDKQECDIPSLTSGEPHPMDDRLPS
LELKNTLRILEGACAQLCVTLAPPAHTMLNYSMDVLVPSCISTVIQAGVA
PLLAKHPKGLHIDVLSKETGIHPQKLATILRLLILNYCFQEVESNVFANN
RLSLTLLPETSVVDILDLKTGEMHRKATLWVYDALVDPDFGPTYDGNKSP
LVYALRREGFDGSLYDYLQTQPGAVARFARAMLGFSVSRGLMNLLNVFPW
QELAPGSTVCDLGGGNGNTSIEIAKKFPHLKVHLQDLPDTIEEAKVFWKE
EYPDAIKDSRVAFTPIDFFKQAPVPDQDIYYISQIVHNWGDEDCITLLKN
IRSAMSPKSRLLINDYLASHLDKTSIANQHPSLPRAPYPLSPGFGRGMAR
TYTGDYTMLVVCNSRERSLEDFIELCSAADLKFVRVWDLAETSVTEFVPA
Ligand information
Ligand IDORN
InChIInChI=1S/C5H12N2O2/c6-3-1-2-4(7)5(8)9/h4H,1-3,6-7H2,(H,8,9)/t4-/m0/s1
InChIKeyAHLPHDHHMVZTML-BYPYZUCNSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C[C@@H](C(=O)O)N)CN
CACTVS 3.370NCCC[CH](N)C(O)=O
CACTVS 3.370NCCC[C@H](N)C(O)=O
ACDLabs 12.01O=C(O)C(N)CCCN
OpenEye OEToolkits 1.7.6C(CC(C(=O)O)N)CN
FormulaC5 H12 N2 O2
NameL-ornithine
ChEMBLCHEMBL446143
DrugBankDB00129
ZINCZINC000001532530
PDB chain8pha Chain A Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8pha A Novel O - and S -Methyltransferase from Pleurotus sapidus Is Involved in Flavor Formation.
Resolution2.02 Å
Binding residue
(original residue number in PDB)		H375 S380 S423 E425
Binding residue
(residue number reindexed from 1)		H370 S375 S418 E420
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008171 O-methyltransferase activity
Biological Process
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8pha, PDBe:8pha, PDBj:8pha
PDBsum8pha
PubMed38462720
UniProtA0A067NAT9

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