Structure of PDB 8pe3 Chain A Binding Site BS01

Receptor Information
>8pe3 Chain A (length=386) Species: 1308 (Streptococcus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GANAMGVLISAVGDTDPFRNFHDGALIHIARKYRPEKVILIFSEHTAKKQ
GNIEKALFSIAPNYEPELIIHDPIISDNEVHIFDVMFQRFSDILQEYYTK
EDEFILNLSSATPQIKSALFVINRLNGINVKAVQVSSPEHASNENIGHDN
DENIDELIEVNKDNKVNFIDRTIEDNAEKFSQALLKKTARDFIEKFDYKA
ALDILDQLSDFPNLKSVREEIRDVVNCLSKQDVPKGLRHKKLKEEEQKIL
SAYLTIELQRERGNVSESFIRIKNLTEFILEDYIKKRYPGLIDEYCEDYL
SLFDYSKLLKATKEFKLKRTIAPIIDMNSSRNKVAHSLSPLDSDAVKQLG
IAMKTLKTLVREQYHFSQSDFNFYQDLNKILLTKLN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pe3 Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open.
Resolution1.96 Å
Binding residue
(original residue number in PDB)		G9 D10 T11 R15 D19 S39 H41 D73 H77 S105 A107 T108 P109 K112 V131 P134 H136 A137 S138 N139
Binding residue
(residue number reindexed from 1)		G13 D14 T15 R19 D23 S43 H45 D77 H81 S109 A111 T112 P113 K116 V135 P138 H140 A141 S142 N143
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8pe3, PDBe:8pe3, PDBj:8pe3
PDBsum8pe3
PubMed37747760
UniProtA0A0A7HFE6|CSM6B_STRTR CRISPR system endoribonuclease Csm6' (Gene Name=csm6')

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