Structure of PDB 8pdo Chain A Binding Site BS01

Receptor Information
>8pdo Chain A (length=351) Species: 694067 (Human metapneumovirus CAN97-83) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LQGIHLSDLSYKHAILKESQYTIKRDVGTTTAVTPSSLQQEITLLCGEIL
YAKHADYKYAAEIGIQYISTALGSERVQQILRNSGSEVQVVLTRTYSQML
DIHGVEKSWVEEIDKEARKTMATLLKESSGNIPQNQRPSAPDTPIILLCV
GALIFTKLASTIEVGLETTVRRANRVLSDALKRYPRMDIPKIARSFYDLF
EQKVYHRSLFIEYGKALGSSSTGSKAESLFVNIFMQAYGAGQTMLRWGVI
ARSSNNIMLGHVSVQAELKQVTEVYDLVREMGPESGLLHLRQSPKAGLLS
LANCPNFASVVLGNASGLGIIGMYRGRVPNTELFSAAESYAKSLKESNKI
N
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8pdo Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		K171 A173 S174 R185 R186 R189 Q250 G255 T257 W261 S314 I334 M337 Y338 R339
Binding residue
(residue number reindexed from 1)		K157 A159 S160 R171 R172 R175 Q236 G241 T243 W247 S300 I320 M323 Y324 R325
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8pdo, PDBe:8pdo, PDBj:8pdo
PDBsum8pdo
PubMed37993464
UniProtQ6WBA1|NCAP_HMPVC Nucleoprotein (Gene Name=N)

[Back to BioLiP]