Structure of PDB 8p9x Chain A Binding Site BS01

Receptor Information
>8p9x Chain A (length=239) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRRLSMLPHLADLVSY
SIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSW
SCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAI
CLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLA
DLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEVS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8p9x A vitamin D-based strategy overcomes chemoresistance in prostate cancer.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		I270 K274 R280 I288 K292 P442 E446 V452 S453
Binding residue
(residue number reindexed from 1)		I56 K60 R66 I74 K78 P228 E232 V238 S239
External links
PDB RCSB:8p9x, PDBe:8p9x, PDBj:8p9x
PDBsum8p9x
PubMed38982588
UniProtQ9PTN2|VDRA_DANRE Vitamin D3 receptor A (Gene Name=vdra)

[Back to BioLiP]