Structure of PDB 8p9o Chain A Binding Site BS01

Receptor Information
>8p9o Chain A (length=253) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALEARLEQASILKKVVDAIKDLVQDCNFDCNDSGIALQAMDNSHVALVSM
MLKAEGFSPYRCDRNIALGVNLTSLTKVLRAAQNEDILTLKAEDAPDVLN
LVFESSETDRISEYDLKLMDIDQEHLGIPETEYAATITMPSNEFKRITTD
LMAMSESVTIEANGVKFSCQGDIGNGSVTLRQHTNVEKPNESIEIELSEP
VSLTFSLKYLVNFCKASALSNTVKICLSNEVPLLVEYSLGGSSYLRFYLA
PKI
Ligand information
>8p9o Chain P (length=11) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
QGSIMSWFAKK
Receptor-Ligand Complex Structure
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PDB8p9o Canonical binding of Chaetomium thermophilum DNA polymerase delta/zeta subunit PolD3 and flap endonuclease Fen1 to PCNA
Resolution2.45 Å
Binding residue
(original residue number in PDB)		M40 H44 V45 L47 H125 L126 G127 P129 E232 P234 Y250 A252 P253 K254 I255
Binding residue
(residue number reindexed from 1)		M40 H44 V45 L47 H125 L126 G127 P129 E230 P232 Y248 A250 P251 K252 I253
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030337 DNA polymerase processivity factor activity
Biological Process
GO:0006260 DNA replication
GO:0006272 leading strand elongation
GO:0006275 regulation of DNA replication
GO:0006281 DNA repair
GO:0006298 mismatch repair
GO:0019985 translesion synthesis
Cellular Component
GO:0005634 nucleus
GO:0043626 PCNA complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8p9o, PDBe:8p9o, PDBj:8p9o
PDBsum8p9o
PubMed38223238
UniProtG0SF70|PCNA_CHATD Proliferating cell nuclear antigen (Gene Name=CTHT_0061010)

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