Structure of PDB 8oqc Chain A Binding Site BS01

Receptor Information
>8oqc Chain A (length=124) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHES
LADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTT
QANKHIIVACEGNPYVPVHFDASV
Ligand information
Ligand IDD1O
InChIInChI=1S/3C2H4O2.2H2O.2Rh/c3*1-2(3)4;;;;/h3*2H,1H3;2*1H2;;/q3*-2;;;2*+4/p-2
InChIKeyWOIABTFBXKXYRQ-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7CC1O[Rh]23(OC(O[Rh]2(O1)(OC(O3)C)O)C)O
CACTVS 3.385C[CH]1O[Rh]23(O)O[CH](C)O[Rh]2(O)(O1)O[CH](C)O3
CACTVS 3.385C[C@H]1O[Rh]23(O)O[C@@H](C)O[Rh]2(O)(O1)O[C@H](C)O3
FormulaC6 H14 O8 Rh2
Nametri-(mi2-acetato-(O, O')-diaqua-dirhodium(II, II)
ChEMBL
DrugBank
ZINC
PDB chain8oqc Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8oqc Cross-Linked Crystals of Dirhodium Tetraacetate/RNase A Adduct Can Be Used as Heterogeneous Catalysts.
Resolution1.5 Å
Binding residue
(original residue number in PDB)		K7 Q11 V118 H119
Binding residue
(residue number reindexed from 1)		K7 Q11 V118 H119
Annotation score1
Enzymatic activity
Enzyme Commision number 4.6.1.18: pancreatic ribonuclease.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity
GO:0004522 ribonuclease A activity
GO:0004540 RNA nuclease activity
GO:0005515 protein binding
GO:0016829 lyase activity
Biological Process
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8oqc, PDBe:8oqc, PDBj:8oqc
PDBsum8oqc
PubMed37144589
UniProtP61823|RNAS1_BOVIN Ribonuclease pancreatic (Gene Name=RNASE1)

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