Structure of PDB 8ooy Chain A Binding Site BS01

Receptor Information
>8ooy Chain A (length=604) Species: 866768 (Escherichia coli 'BL21-Gold(DE3)pLysS AG') [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPHDNYVTILDEETLKAWIAKLEKAPVFAFDTETDSLDNISANLVGLSFA
IEPGVAAYIPVAHDYLDAPDQISRERALELLKPLLEDEKALKVGQNLKYD
RGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITFE
EIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPLN
VFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELTLRLAELEKKAHEIA
GEEFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLP
KVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDP
NLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRDKGLL
TAFAEGKDIHRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLA
RQLNIPRKEAQKYMDLYFERYPGVLEYMERTRAQAKEQGYVETLDGRRLY
LPDIKSSNGARRAAAERAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRV
RMIMQVHDELVFEVHKDDVDAVAKQIHQLMENCTRLDVPLLVEVGSGENW
DQAH
Ligand information
>8ooy Chain T (length=26) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aacgtcgtgactgggaaaaccctggc
..........................
Receptor-Ligand Complex Structure
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PDB8ooy A four-point molecular handover during Okazaki maturation.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		S582 K584 K643 T664 T666 T672 D673 N675 Y766 M768 S769 F771 R775 Q776 R781 R841 Q849
Binding residue
(residue number reindexed from 1)		S258 K260 K319 T340 T342 T348 D349 N351 Y442 M444 S445 F447 R451 Q452 R457 R517 Q525
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:8ooy, PDBe:8ooy, PDBj:8ooy
PDBsum8ooy
PubMed37620586
UniProtP00582|DPO1_ECOLI DNA polymerase I (Gene Name=polA)

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