Structure of PDB 8kdx Chain A Binding Site BS01

Receptor Information
>8kdx Chain A (length=60) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGTTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETG
YIPSNYVAPV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8kdx Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current.
Resolution1.01 Å
Binding residue
(original residue number in PDB)
Y91 D118 W119 P134 N136 Y137
Binding residue
(residue number reindexed from 1)
Y10 D37 W38 P53 N55 Y56
Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
External links
PDB RCSB:8kdx, PDBe:8kdx, PDBj:8kdx
PDBsum8kdx
PubMed38218365
UniProtP06241|FYN_HUMAN Tyrosine-protein kinase Fyn (Gene Name=FYN)

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