Structure of PDB 8k4d Chain A Binding Site BS01

Receptor Information

>8k4d Chain A (length=920) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVT
AEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVL
VRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVN
VALNLSINMDNTQRQYEAERNKANERLELLLQKRKELQENQDEIENMMNA
IFKGVFVHRYRDAIAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMH
DKQGEVRLKCLTALQGLYYNKELNSKLELFTSRFKDRIVSMTLDKEYDVA
VQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLF
SQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMNSLL
LEEPLSALTDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLTAKEKKT
QLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRL
EKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRS
QLIDELADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSK
WDLFACNYKLLKTGIENGDMPEQIVIHALQCTHYVILWQLAKISSSTKED
LLRLKKQMRVFCQICQHYLTNVNTTVKEQAFTILCDILMIFSHQIMSGGR
DMLEPLVYTPDSSLQSELLSFILDHVFIEQQEDEASKIEALHKRRNLLAA
FCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAK
TLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFLKTREAIA
MLHKDGIEFAFKEPNPQGEPLNLAFLDILSEFSSKLLRQDKRTVYVYLEK
FMTFQMSLVWLPLMSYRNSL

Ligand information

>8k4d Chain C (length=9) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

IDVFDFPDN

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	8k4d The CENP-O complex links inner kinetochore to centromere cohesion
Resolution	3.52 Å
Binding residue (original residue number in PDB)	D326 W334 L366 R370 F371
Binding residue (residue number reindexed from 1)	D239 W247 L279 R283 F284

External links

PDB	RCSB:8k4d, PDBe:8k4d, PDBj:8k4d
PDBsum	8k4d
PubMed
UniProt	Q8N3U4\|STAG2_HUMAN Cohesin subunit SA-2 (Gene Name=STAG2)

[Back to BioLiP]