Structure of PDB 8jtj Chain A Binding Site BS01 |
| >8jtj Chain A (length=1042) Species: 1422 (Geobacillus stearothermophilus)
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MRYKIGLDIGITSVGWAVMNLDIPRIEDLGVRIFDRAENPQTGESLALPR
RLARSARRRLRRRKHRLERIRRLVIREGILTKEELDKLFEEKHEIDVWQL
RVEALDRKLNNDELARVLLHLAKRRGFKSNRKSKENSTMLKHIEENRAIL
SSYRTVGEMIVKDPKFALHKRNKGENYTNTIARDDLEREIRLIFSKQREF
GNMSCTEEFENEYIAIWASQRPVASKDDIEKKVGFCAFEPKEKRAPKATY
TFQSFIAWEHINKLRLISPSGARGLTDEERRLLYEQAFQKNKITYHDIRT
LLHDTYFKGIVYDRQNENIRFLELDAYHQIRKAVDKVYGKEKSSSFLPID
FDTFGYALTLFKDDADIHSYLRNEYEQNGKRMPNLANKVYDNELIEELLN
LSFTKFGHLSLKALRSILPYMEQGEVYSSACERAGYTFTGPKKKQKTMLL
PNIPPIANPVVMRALTQARKVVNAIIKKYGSPVSIHIELARDLSQTFDER
RKTKKEQDENRKKNETAIRQLMEYGLTLNPTGHDIVKFKLWSEQNGQPIE
IERLLEPGYVEVDAVIPYSRSLDDSYTNKVLVLTREREKGNRIPAEYLGF
ETFVLTNSKKKRDRLLRLHYDENEETEFKNRNLNDTRYISRFFANFIREH
LKFAESDDKQKVYTVNGRVTAHLRSRWEFNKNREESDLHHAVDAVIVACT
TPSDIAKVTAFYQRREQNKELAKKTEPHFPQPWPHFADELRARLSKHPKE
SIKALNLGNYDDQKLESLQPVFVSRMPKRSVTGAAHQETLRRYVGIDERS
GKIQTVVKTKLSEIKLDASGHFPMYGKESDPRTYEAIRQRLLDPKKAFQE
PLYKPKKNGEPGPVIRTVKIIDTKNQVIPLNDGKTVAYNSNIVRVDVFEK
DGKYYCVPVYTMDIMKGILPNKAIEPNKPYSEWKEMTEDYTFRFSLYPND
LIRIELPREKTVKTAAGEEINVKDVFVYYKTIDSANGGLELISHDHRFSL
RGVGSRTLKRFEKYQVDVLGNIYKVRGEKRVGLASSAHSKPG |
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| PDB | 8jtj Cryo-EM structure of GeoCas9-sgRNA-DNA ternary complex |
| Resolution | 3.08 Å |
Binding residue
(original residue number in PDB) | S45 L46 A47 R50 R51 A53 R54 R57 R58 R59 L60 R61 R62 K64 H65 R69 R72 R76 D96 W98 K123 R124 R125 G126 K174 R175 N176 K177 E179 R225 P226 V227 K235 H264 F333 Y439 R475 T478 K489 R661 G813 A814 H816 L820 R822 K838 Y855 E858 K890 K891 P897 V898 I899 R900 T901 K903 D916 T919 M949 Q1049 V1059 R1060 S1069 H1072 S1073 K1074 P1075 G1076 |
Binding residue
(residue number reindexed from 1) | S45 L46 A47 R50 R51 A53 R54 R57 R58 R59 L60 R61 R62 K64 H65 R69 R72 R76 D96 W98 K123 R124 R125 G126 K170 R171 N172 K173 E175 R221 P222 V223 K231 H260 F321 Y427 R463 T466 K477 R631 G783 A784 H786 L790 R792 K808 Y825 E828 K856 K857 P863 V864 I865 R866 T867 K869 D882 T885 M915 Q1015 V1025 R1026 S1035 H1038 S1039 K1040 P1041 G1042 |
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