Structure of PDB 8joy Chain A Binding Site BS01
Receptor Information
>8joy Chain A (length=216) Species:
9606
(Homo sapiens) [
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HLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYG
LGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSL
MKKITLLKYFRNYMSEHLLKAGANITPARLPYLRTWFRTRSAIILHLSNG
SVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELAS
RLRYARTMVDKLLSSR
Ligand information
>8joy Chain B (length=7) Species:
10617
(Human papillomavirus 4) [
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PKTSTPR
Receptor-Ligand Complex Structure
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PDB
8joy
Crystal Structures of Plk1 Polo-Box Domain Bound to the Human Papillomavirus Minor Capsid Protein L2-Derived Peptide.
Resolution
2.61 Å
Binding residue
(original residue number in PDB)
K413 W414 D416 Y485 S487 E488 H489 L490 L491 R516 H538 K540 R557
Binding residue
(residue number reindexed from 1)
K41 W42 D44 Y113 S115 E116 H117 L118 L119 R138 H160 K162 R179
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:8joy
,
PDBe:8joy
,
PDBj:8joy
PDBsum
8joy
PubMed
37684534
UniProt
P53350
|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)
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